Ralph@home is the official alpha test project for Rosetta@home. New application versions, work units, and updates in general will be tested here before being used for production on Rosetta@home. The goal for Ralph@home is to improve Rosetta@home.

Please consider the following before deciding to join Ralph@home:

• Since this project is a testing environment, applications and work units may be unstable at times.
• Credits and other competitive statistics do not mean anything in this test project. Credits may be lost due to instabilities and may be reset at any time for testing.
• There will not be a continual flow of work units. Work units will be issued only when necessary for testing.
• We urge participants to not abort work units to help with testing.

Follow us on Twitter: @rosettaathome

Ralph@home and Rosetta@home are not for profit.

Rosetta version 4.29 released for testing
The Rosetta application has been updated to include fixes to the core algorithm for protein modeling. Due to how the algorithm interacts internally, we will leave graphics disabled for this version. Please report any issues in the discussion thread here: https://ralph.bakerlab.org/forum_thread.php?id=944
6 Aug 2024, 21:34:56 UTC · Discuss

New application: RoseTTAFold All-Atom
Starting this week, we will begin testing RoseTTAFold All-Atom, our state-of-the-art application designed to predict the structures of proteins in complex with ligands such as DNA and other biological molecules. It also models post-translational modifications. We are initially targeting only Windows machines with or without Nvidia GPUs for this test. Please report any issues in the discussion thread here: https://ralph.bakerlab.org/forum_thread.php?id=928
21 May 2024, 23:49:48 UTC · Discuss

Rosetta version 4.27 released for testing
The Rosetta application has been updated to include fixes to the GALigandDock protocol. Please report any issues in the discussion thread here: https://ralph.bakerlab.org/forum_thread.php?id=906
16 Sep 2023, 2:29:02 UTC · Discuss

Rosetta version 4.24 released for testing
The Rosetta application has been updated to fix bugs that we have observed from 4.23. Please report any issue in the discussion thread here: https://ralph.bakerlab.org/forum_thread.php?id=894
28 Mar 2023, 6:15:41 UTC · Discuss

Rosetta version 4.23 released for testing
The Rosetta application has been updated to include a protocol named GALigandDock that will be used to screen an ultra-large library of small molecules for drug discovery. Please report any issue in the discussion thread here: https://ralph.bakerlab.org/forum_thread.php?id=892
10 Mar 2023, 22:16:18 UTC · Discuss

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